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412 Minihepcidins, which are hepcidin agonists, improve anemia and iron overload in young -thalassemia model Hbb th3/+ mice, and enhance erythropoiesis without altering the beneficial effect of the iron chelating agent DFO on iron overload in older -thalassemia mice

These findings highlight the potential role of the gut microbiome in enhancing the hosts antiviral immune competence

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Yendamuri S, Vaporciyan AA, Zaidi T, Fernandez R, Rice DC , Spitz M, Swisher S, Walsh GL, Roth JA, Katz RL