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The TRIUMPH-4 trial revealed a notable incidence of dysesthesia, an abnormal sensation affecting touch perception that can cause numbness, tingling, or unusual skin sensitivity

Oct 2005;16(10):577-586

10.1158/1078-0432.ccr-19-3034

The immune cells have a certain demand for glutamine, and a decrease in glutamine levels can threaten the integrity and function of immune cells [149]