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Avoids Serious Complications In patients with severe anaemia, intensive treatment with B12 may result in a sudden drop in potassium (hypokalaemia), which can cause muscle weakness or an irregular heartbeat

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This observation is consistent with previous studies [67-69]

Crystals of ShHTL1 were grown by mixing 0.45 L of purified ShHTL1 protein solution (15.0 mg mL 1 ) with 0.45 L of reservoir solution containing 100 mM Tris (pH 8.5), 150 mM MgCl 2 , and 23% (w/v) PEG6000 and allowing the drop to equilibrate at 5 C

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