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[4] The proposed mechanism of action, based only on preclinical animal studies, involves potential modulation of growth factor pathways, particularly vascular endothelial growth factor (VEGF), which may promote angiogenesisthe formation of new blood vessels

B.CarrascoM

So it may be good to check your homocysteine and MMA levels at least once, even if you take vitamin B12 supplements, just to avoid any unpleasant surprises