[DOI] [PMC free article] [PubMed] [Google Scholar] 100.Zhao X., Bey E.A., Wientjes F.B., Cathcart M.K
A potential treatment strategy for TMJ OA could be the injection of the ferroptosis inhibitor Lip-1, which successfully reduced chondrocyte ferroptosis, restored mitochondrial function, decreased ROS and lipid peroxidation, and improved the integrity of the cartilage matrix [100]
Prescott in the Lancet and others questioning the ethics of with-holding treatment
Michelucci et al., SARS-CoV-2 ORF3a accessory protein is a water-permeable channel that induces lysosome swelling, Communications Biology, doi:10.1038/s42003-024-07442-5
found that exogenous -KG mimics glutaminase-mediated ferroptosis, while using a transaminase inhibitor, amino-oxyacetate (AOA), reverses ferroptosis [85, 86]