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These results show that FOXO4-DRI caused nuclear exclusion of Ser15-phospho-p53 and induced apoptosis in senescent TM3 Leydig cells, and that it acted selectively against senescent cells

People with stomach ulcers often have diets low in fiber and antioxidants

Mitochondria as determinants of reproductive senescence and competence: implications for diagnosis of embryo competence in assisted reproduction

Fatigue: The bodys adjustment to lower food intake and metabolic changes can cause temporary tiredness

doi: 10.3389/fonc.2026.1748136 Received 18 November 2025 Revised 23 March 2026 Accepted 24 March 2026 Published 30 April 2026 Volume 16 - 2026 Edited by Pierfranco Conte, University of Padua, Italy Reviewed by Valeria Conti, University of Salerno, Italy T Mohan Viswanathan, Karpagam Academy of Higher Education, India Updates Copyright 2026 Talath, El-Tanani, Wali, Rabbani, Bhongande, Ibraheem, Avagimyan, Hoffmann, Ilias, Ispas, Viviana, Paczkowska and Rizzo