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Multi-omics integration was conducted to reveal core regulatory networks, and mechanistic validation focused on the expression of Nrf2, HO-1, and GPX4

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In addition, our differential expression analysis identified upregulation of a considerable number of transcripts related to ribosomal proteins in Gclc fl/fl MZB compared to Gclc fl/fl FoB (Supplementary Fig

Moreover, each of these aspects is influenced by different processes, such as oxidative stress