Smoke can irritate your eyes and respiratory system
In 2013, for example, there were 111 calls in Ontario about cigarette poisonings, compared to only 10 e-cigarettes
Poor sleep over a long period can lead to other physical and mental health issues
My boyfriend and I were raised in totally different environments and, while he was having these pschodelic experiences with his brothers and friends, I was being fed (in his words) anti-drug propaganda and occupied myself being the good girl

The PM investigators [18] reported a few minor differences in the biological activity of the rats exposed to cigarettes with the additives, but dismissed these differences as following no clear pattern, suggesting they are due to statistical inference. The overall conclusion, reported in the paper's abstract is that the data [from a 90-d inhalation study] indicate that the addition of the 333 commonly used ingredients, added to cigarettes in three groups, did not increase the inhalation toxicity of the smoke. The animal toxicology results [18] reported from Project MIX were based on a small number of rats in each experiment (usually nine), raising the possibility that the failure to detect statistically significant changes in the end points were due to underpowering the experiments rather than lack of a real effect