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Research focuses on its effects on soft tissue recovery and gastrointestinal health

stomach pain increased salivation quick heavy breathing tachycardia 1) hypertension headache pale skin muscle fasciculations & weakness seizures Late inhibitory phase (including Muscle paralysis & Ganglionic blockade) (30 mins to an hour): bradycardia diarrhea dyspnea shallow breathing hypotension lethargy / coma severe muscle weakness & paralysis respiratory failure (paralysis of diaphragm) Pharmacokinetics: Nicotine is well absorbed through the skin Major drug Interactions: May alter the pharmacokinetics of certain concomitant medications, such as tricyclic antidepressants and theophylline

(PubMed) Breithaupt-Grogler K, Niebch G, Schneider E, et al

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