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Modifications in lipid metabolism of GDM maternity, as indicated by altered triglyceride and cholesterol levels [80], may intensify lipid peroxidation, thereby augmenting oxidative stress within the placenta

Similar to DNA, RNA can also suffer from oxidative damage, where 8oxoG in RNA compromises translational fidelity

SARS-CoV-2 infects pulmonary type II alveolar cells because these cells express angiotensin-converting enzyme 2 (ACE2

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Multiple signaling pathways have been implicated in the activation of ROS at these sites, including an increase in calcium, gain of function of oncogenes, as well as changes in oxygen and nutrient levels