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Upregulation of HLADR, intercellular adhesion molecule-1 and E-selectin activates CD2+, CD3+, CD5+, CLA+, CD45RO, HLA-DR, CD25 (IL-2 receptor) and CD27 expressing T cells [2]

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This neuroimmune regulatory pathway was critical for reducing systemic responses and lung injury in a polymicrobial sepsis model and involved downstream 1-adrenergic and opioid receptor pathways [115]

3 Inserting exogenous genes 3.1 GM-CSF Induction of immune cells to kill tumor cells is one of the key mechanisms of oncolytic virus anticancer