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Tom Biernacki, DPM Board-certified podiatric surgeon | Balance Foot & Ankle Last reviewed: May 2026 Quick answer: Burning feet syndrome (Grierson-Gopalan syndrome) is a symptom, not a diagnosis the burning, heat, and night-time tingling almost always trace to a nerve or metabolic cause: most often peripheral neuropathy from diabetes, a B-vitamin deficiency, tarsal tunnel compression, or small-fiber neuropathy

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#10 Medical Conditions Certain medical conditions such as diabetes, liver diseases, chronic kidney disease, and neurodegenerative disorders can hinder glutathione synthesis or utilization

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