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Oxidative stress also activates the Kelch-like ECH-associated protein 1 (Keap1)-Nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) redox regulator pathway, releasing Nrf2 to regulate the expression of genes that control antioxidant, inflammatory and immune system responses, facilitating GSH activity

When cooking with Garlic, never let it reach over 140 degrees

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To investigate the mechanisms by which ibuprofen affect mouse liver, a quantitative LC-MS/MS technique using tandem mass tag (TMT) labeling was carried out to measure whole liver proteome changes after short-term (7 days) treatment of ibuprofen (100 mg/kg/day)

doi: 10.1038/nature13148 54