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In fact, the first defences against poison-murder were not legislative, but scientific

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Assuming a consumption of 100 mg of liquid refill in 20 puffs of 70 mL (mean amount determined during all of the experiments), the formaldehyde content in commercial liquid refills ranged from 0.5 to 22 g, while the acetaldehyde content was between 0.9 and 18 g

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If the DNA adducts persist unrepaired, they can cause miscoding during DNA replication as bypass polymerases catalyze the insertion of the wrong base opposite the adduct