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Growth of this strain containing the gene circuit in the presence of an inducer activates transcription of the reporter gene, producing a detectable signal, as long as the inducer exceed a specified concentration, which defines the limit of detection (LOD) or sensitivity of the circuit

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Arzani, M., et al

An oral version of the drug is also in development to improve patient convenience

A: Many patients feel a boost in energy within hours, while mood and metabolism benefits may develop over several days