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Animal data is a necessary first step, but its far from sufficient on its own to draw conclusions about a drugs effectiveness and safety in humans

And people who are overweight or obese are at greater risk of developing high blood pressure

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However, significant translational barriers remain: no human pharmacokinetic data, high synthesis cost, unknown long-term safety, and the absence of clinical trials

Plasma membrane phosphatidylinositol 4-phosphate is necessary for virulence of Candida albicans