Notably, incubation of AX with L-cysteine (with the nonprotected-amino group) did not afford DKP, but mainly, the product corresponding to the aminolysis of the -lactam ring, which remained conjugated to the amino group of cysteine through an amide bond ( Figure S8 )
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Vial intact, good cold packing.
Refractive index (at 20C): 1.3345 1.3350
Since several ATGs and lysosomal cathepsin proteases depend on cysteines for their activities they can be the sensors or transducers of changes in the intracellular redox state through mechanisms involving redox signaling
