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Non-mitochondrial ROS sources in diabetes Regardless of whether excessive ROS formation is the primary initiator or accompanying factor in the pathogenesis of diabetes mellitus, oxidative stress plays a key role in the organ complications such as cardiovascular problems, neurological problems (stroke), diabetic retinopathy, nephropathy, and neuropathy

Histamine production leads to hives formation

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Several studies suggest that Glutathione deficiency is the most reasonable explanation for the severe manifestation of coronavirus

10.1016/j.pharmthera.2024.108787 26 KanemaruE.ShimodaK.MarutaniE.MoritaM.MirandaM.MiyazakiY.et al (2024)