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The tissue-specific effect of l-carnitine was found in many experiments in mammals or fish, in which the carnitine content of muscle was relatively stable, whereas the liver was more sensitive to carnitine supplementation or deficiency ( Reference Li, Li and Qin 32 , Reference Morand, Bouitbir and Felser 48 , Reference Wchter, Vogt and Kreis 49 )
There is substantial evidence that the expression of SOCS3 protein increases with aging in several cells/tissues, such as rat myocardium [162], hypothalamus [163], and human blood mononuclear cells [164] as well as human sarcopenic skeletal muscles [165] and the brains of Alzheimers patients [166]
Il glutatione nella terapia delle epatopatie croniche steatosiche [glutathione in the treatment of chronic fatty liver diseases]
Many factors, including oxidative stress and intermediate oligomer conformation, play important roles in the pathogenesis of Parkinsons disease in different metabolic pathways