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The dose escalation protocol matters ENORMOUSLY here: Rushing the titration is where most people run into trouble with GI distress that could otherwise be prevented with patience and proper medical oversight

The additional NSAID and anti-nausea medications will help with pain relief and reduce feelings of nausea

Interaction between the transactivation domain of p53 and PC4 exemplifies acidic activation domains as single-stranded DNA mimics

doi: 10.1038/ijo.2013.139

Common side effects & management Your doctor might hold off on raising the dose if any of the following occur: Lingering nausea, vomiting, or other ongoing side effects