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doi:10.1111/jpi.12172

Additionally, activation of the aryl hydrocarbon receptor (AHR) signaling pathway has been implicated in the transcriptional and possibly epigenetic regulation of both CYP27B1 and CYP24A1 ( 3.2 Dysregulation of vitamin D metabolism in chronic kidney disease In the context of CKD, the regulatory network governing vitamin D metabolism becomes markedly disrupted

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Furthermore, Rac1 plays a crucial role in specific brain functions, including neuronal migration, synaptic plasticity, and memory formation, through its regulation of actin dynamics in neurons