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In conclusion we can assess that glutathione metabolism is differently affected in the two resistant strains to the examined drugs and that in CO23RFLC, glutathione system is an important part of the overall organization of this cells for resistance

More hydrophilic conjugates would be expected to display a decreased binding to plasma proteins, but published investigations suggested that a change in plasma protein binding was dependent on the polyphenol and its type and position of conjugation (5962)

Timing: Set administration intervals that fit the expected pulse pattern being studied

The marks are more spread out, making small doses easier to measure precisely

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