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With respect to the substantial similarity criteria, the applicant stated that SER-109 is not substantially similar to other currently available technologies because SER-109 does not have the same or similar mechanism of action as any currently FDA-approved CDI treatment and does not involve treatment of the same or similar type of disease or patient population as there are currently no approved therapies indicated to repair a disrupted microbiome as a treatment intervention to prevent recurrence in patients with rCDI

Studies on CLA: Research confirms that CLA helps reduce fat deposits and increase muscle mass

8A and B indicated a marked reduction in DHRS7 levels in tumor tissues when compared to normal counterparts

Bioprocess Biosyst Eng 32(6):729735

Result Ipamorelin was highly potent for GH release and, uniquely among GHRPs tested, did not raise ACTH or cortisol above GHRH baseline even at doses 200 the GH-release ED