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However, even when combined with chemotherapy, personalized vaccination did not result in significant survival differences, as demonstrated in the treatment of CRPC with personalized autologous dendritic-cell-based cancer vaccine (DCvac) plus docetaxel [171]

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The burden of Alzheimer's disease The long duration of illness before death contributes significantly to the public health impact of Alzheimer's disease because much of that time is spent in a state of severe disability and dependence

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