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Torres M, Laguna-Barraza R, Dalmases M, et al

Preclinical studies have investigated the synergies between these two peptides, suggesting that: BPC-157 provides broad signaling modulation through growth factor receptor upregulation and NO pathway activation TB-500 supplies the cytoskeletal machinery for cellular migration and matrix reorganization Combination effects may target multiple stages of tissue repair simultaneously from initial signaling through structural remodeling 6

Results were validated in an external validation set

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J Pharmacol Exp Ther 2002