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Funding This work is funded by KBRI (25-BR-02-01, 25-BR-05-01), the Ministry of Trade, Industry and Energy (RS-2024-00507932), and by the Ministry of Science and ICT (2022R1A5A202954611 and RS-2025-16065563)

Furthermore, p53 serves as a pivotal regulatory node, inducing apoptosis by upregulating pro-apoptotic factors like PUMA and BAX, while simultaneously promoting ferroptosis by inhibiting SLC7A11.Arrows denote activation

It is recommended to frequently monitor blood levels of potassium and platelet counts in these individuals for early detection and appropriate management of any abnormalities

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