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While it may sound harmless, the challenge can be very dangerous

With regard to distribution , for drugs such as diazepam 1 and penfluridol 5 that are substantially distributed into adipose tissue, greater adiposity is associated with greater storage of the drug in lipid reservoirs, and hence greater availability of the drug for return to blood as blood levels fall due to metabolism

Also, animals fed a high-fat diet have been shown to have increased OxS and dysfunctional mitochondria (136)

M.KleinR.et al (1996)

[DOI] [PubMed] [Google Scholar] 34.Mao L., Yang T., Li X., Lei X., Sun Y., Zhao Y., Zhang W., Gao Y., Sun B., Zhang F