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For in vivo experiments, the closest model would be the C57BL/6 mouse strain though degree of liver injury can vary between sub-strains without change in mechanism

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Histologic and morphometric studies Mice were perfused with ice-cold PBS, followed by Zambonis fixative (0.1 M phosphate buffer containing 2% paraformaldehyde and 15% picric acid) at 5, 8, and 12 W

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