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While the vaccine is highly protective against hospitalization and severe disease, break through infections are now occurring, and virus is being spread by the asymptomatic-vaccinated requiring new mask mandates, that all seem to be linked to the delta variant (50, 51)

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These models could further be leveraged to investigate if NSC-secreted factors modulate the gut microbiomes metabolic output or vice versa, providing a mechanistic link between the central and peripheral effects observed in our study

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