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While I questioned Kunin on the growing popularity of these treatments (she says she sees mostly women and a handful of men, some of whom even come in on their lunch breaks), my arm began to feel tingly, as if I had slept on it for too long

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There are currently two approved FDA treatments for primary hyperoxaluria type 1, Lumasiran and Nedosiran, which target glycolate oxidase and lactate dehydrogenase respectively resulting in reduced endogenous oxalate synthesis 58

This means injecting into the fatty layer of tissue just beneath the skin

de Boer, P