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Analyzed were karyopyknotic cells in the affected brain areas (04), cerebral (NTP-7, Level 3), cerebellar cortex (NTP-7, Level 6), and hippocampus, thalamus, and hypothalamus (NTP-7, Level 3) as follows (score 0 indicates no change): score 1: a few karyopyknotic of neuronal cells (20%)

740 Activity assays reveal that as expected, Zn II binding to site 2 inhibits turnover by QueD2, which suggests that the active site 1 may well be conformationally plastic or dynamically heterogeneous and must fold to accommodate substrate, in striking contrast to the housekeeping enzyme QueD

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Pull the needle out on the same path you used going in