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the higher the dose, the more risky 00:11:43 Testosterone & Women, SHBG For health optimization, testosterone is just as important for women to know as it is for men For preventing diseases like breast cancer and osteoporosis, estrogen and progesterone are more important Women think they have barely any testosterone because most tests measure free testosterone, which is the smallest proportion SHBG (sex hormone binding globulin) binds androgens in order of strength: DHT, the strongest, then testosterone, then DHEA, then estrogens like estradiol, the weakest When you look at total testosterone, almost all women actually have way more testosterone than estradiol

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| 2025 | Curr Rev Musculoskelet Med The FDA placed it on the Category 2 bulk drug list in 2023 and WADA banned it for athletes in 2022

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But if you look closer, they operate through very different biological pathways

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Sustained activation of this pathway in healthy individuals raises theoretical cancer concerns

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In hypothyroidism, levothyroxine mimics the natural production of T4

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