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MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4

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Rats underwent intravenous administration of 4.5 mg/kg panduratin A, a single oral administration of 45 mg/kg panduratin A, or a multiple oral administration of 45 mg/kg panduratin A-consisted fingerroot extract for 7 consecutive days

If methylfolate is short, SAMe production drops, methylation slows, and you get downstream consequences in creatine production, energy and endurance, tissue repair, cell membrane signaling, and DNA-level gene expression

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