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It has been also shown to upregulate mitochondrial transcription factor A (TFAM) (Sreekumar et al., 2016), known to play a crucial role in stabilizing mtDNA through the formation of nucleoids, which are important to counteract mtDNA release (Li F et al., 2020), which serve as markers of oxidative stress (e.g., Lei and Rao, 2022)

Conversely, in neuronal networks treated with d-lactate we observed an increase in apoptosis and cell death as compared to not treated cultures

Mental health changes: Tell your healthcare provider right away about any new or worsening depression, mood changes, or thoughts of suicide or self-harm

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