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People experiencing problems with a product labeled as CBD can reach a local poison control center by calling 1-800-222-1222.

Our second evidence synthesis was a systematic review of primary studies on the benefits and harms of e-cigarettes for smoking cessation,23 which updated an existing Cochrane review from 2016.86 Although Cochrane has since transformed its review into a living systematic review,24 it had not yet done so when we developed our evidence review protocol.87 The Evidence Review and Synthesis Centre at the University of Ottawa conducted the systematic reviews according to our protocol.87 Peer-reviewed search strategies (using the Peer Review of Electronic Search Strategies checklist88) were conducted in MEDLINE, Embase, PsycINFO, and the Cochrane Library in September 2020

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It decreases the urge to use tobacco and reduces the severity of nicotine withdrawal symptoms, while also reducing the reward experience of using tobacco.(34) FINAL CONSIDERATIONS The treatment of EC dependence requires an integrated approach combining behavioral interventions and pharmacotherapy, with the ultimate goal being complete nicotine cessation