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The gastric slowing effect is modest, and appetite suppression is mild
According to a study published in PubMed Central (National Institutes of Health), intravenous administration of vitamin B12 provides a faster increase in B12 levels compared to oral supplementation, making it a potentially better option for patients with severe deficiency
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The clinical consequences could range from local inflammation or rash through to serious health issues, such as systemic hypersensitivity, including anaphylaxis, or antibody formation
A deficiency can occur for several reasons, such as pernicious anemia (a condition where the body cannot absorb vitamin B12 from the diet), certain medical conditions (e.g., Crohn's disease, celiac disease), surgical removal of part of the stomach or intestine, or strict vegetarian/vegan diets if not adequately supplemented
