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It stimulates the pulsatile secretion of endogenous GH by the pituitary gland, which in turn activates downstream hepatic production of IGF-1

A 2018 study in Scientific Reports confirmed GHK-Cu's role in activating Wnt/beta-catenin signaling in dermal papilla cells the cells at the base of each follicle that orchestrate the growth cycle

References Sikiric P, Seiwerth S, Grabarevic Z, et al

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