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The TOCC of AA + SO 2 was higher than that of SO 2 alone and lower than that of AA alone because in those conditions, oxygen consumption was only due to the direct reaction of this antioxidant with oxygen and not to polyphenol oxidase activity

An in vitro study using HTR-8/SV neo (HTR-8) cells demonstrated that cigarette smoke exposure resulted in the accumulation of free iron and ROS, which subsequently caused lipid peroxidation and cell death

Not only plant extracts are useful to counteract oxidative damage in NAFLD condition, but also probiotics

ALA is a universal antioxidant because it dissolves in both water-based fluids and fatty tissues, allowing it to move throughout the body in a way that many other antioxidants cannot

Notably, HNF4 expression was also progressively reduced in tumors of the HCC patients with the advancement of the tumor stage in the TCGA LIHC dataset (Supplementary Fig