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GLP-1 therapy, often used to aid in weight loss and blood sugar management, works by mimicking the effects of glucagon-like peptide-1 (GLP-1)

At the molecular level, it modulates the expression of over 4,000 human genes, roughly 6% of the genome, according to a 2012 Broad Institute Connectivity Map analysis published by Pickart, Campbell, and colleagues

While specific protocols vary by laboratory, a common preclinical starting point involves reconstituting the 5mg vial with 1mL of bacteriostatic water to yield a 5mg/mL concentration

While this represents a reasonable duration for clinical trials, it provides limited information about safety with years-long continuous use

The scar tissue can negatively affect how the medication will work