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However, complete recovery may take several months, particularly if the deficiency has been present for a long time

If youre choosing between them for research purposes, AOD-9604 has the stronger evidence base

In summary, the key interactions to consider are pyridoxines reduction of levodopa and anticonvulsant efficacy, niacinamides additive effects on blood pressure, blood sugar, and gout management, and the potential need for B-vitamin repletion in patients on certain medications (diuretics, isoniazid, etc.)

If no improvement appears after six months of consistent use, consider whether the protocol needs modification