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dihexa human clinical trials status 2026

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Notably, BACH1 is traditionally recognized as an angiogenesis inhibitor that regulates HO-1 or VEGF transcription

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However, due to the complex web of factors that influence BAC levels, these methods can only be used as educated guesses

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To put that in perspective, a 10 mg/kg dose in a 250-g rat, scaled allometrically to a 70-kg human using the FDA's body surface area conversion factor of 6.2, translates to roughly 1.6 mg/kg, or 112 mg for a 70-kg person 7

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