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Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short-term simvastatin treatment in humans

Mater 12 (9), e2202766

Anxiogenic effect of subclinical bacterial infection in mice in the absence of overt immune activation

So, you would need to inject 0.5 milliliters of the solution to deliver 500 mcg of vitamin B-12

Consider intramuscular vitamin B 12 injections instead of oral replacement for suspected or confirmed vitamin B 12 deficiency caused by diet if: The person has another condition that may deteriorate rapidly and have a major effect on their quality of life (for example, a neurological or hematological condition such as ataxia or anemia)