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Time-series images were acquired every 5 s (XYZT imaging, stack of 5 confocal images with a size of 512 512 pixels)

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Cancer lesions can develop in two different regions of the prostate gland, most commonly (in ~80% of cases) in the periphery zone, while most of the remaining lesions are found in the transition zone, which is located in the periurethral region (McNeal, 1968, 1988)