If you already know you need a B12 shot, the visit can be straightforward
However, in the pivotal Phase IIb trial, it failed to demonstrate statistically significant weight loss compared to placebo at the primary endpoint, leading the developer (Metabolic Pharmaceuticals Ltd.) to terminate the commercial program
Deficiency is associated with cognitive decline
Picture this: as fat cells expand, they trigger an overproduction of NNMT, slowing down fat cell metabolism the very essence of fat burning
Heres a rough guide that some doctors use, though everyones situation is different: Kidney Function and B12 Dosing Considerations: Above 90 (Normal): Standard B12 doses are usually fine, check levels every 6 months 60-89 (Mild decrease): Might consider slightly lower doses, check every 4 months 30-59 (Moderate decrease): Definitely worth discussing lower doses with your doctor, check every 3 months 15-29 (Severe decrease): High doses probably arent a good idea, monthly monitoring Below 15 (Kidney failure): Avoid high doses entirely, close medical supervision Let me share a story that really opened my eyes to this
