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This nuclear localization in elderly Leydig cells correlated with reduced expression of 3-HSD, a crucial enzyme for testosterone synthesis, suggesting a link between nuclear FOXO4 and age-related decline in testosterone production [2]

J Biol Chem 280:1231612329 Chen YQ, Min C, Sang M, Han YY, Ma X, Xue XQ, Zhang SQ (2010) A cationic amphiphilic peptide ABP-CM4 exhibits selective cytotoxicity against leukemia cells

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Ultimately, our proposed paracrine mechanism would enable rapid, dynamic coordination of intra-islet DA signaling to further fine-tune regulation of insulin and glucagon secretion

Purity Level: 99%