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This means even people with a B12-rich diet can fall short as they get older

Furthermore, the absence of standardized formulations complicates dose uniformity and treatment reproducibility, as differences in concentration, excipients, or stability across preparations can materially influence therapeutic efficacy and safety outcomes

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Furthermore, we found that Sec24C overexpression elevated the expression of SLC7A11 at PM level, but the effect was abrogated upon exposure to Brefeldin A (Fig