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Rovin S, Costich ER, Gordon HA

A 2024 critical review noted that unexpectedly high B12 levels can be further investigated by a clinician if needed, preferably by directly measuring the carrier proteins haptocorrin and transcobalamin rather than relying on the commonly ordered PEG precipitation test, which the authors found nonspecific and potentially misleading (Fedosov, 2024)

Research suggests it promotes blood-vessel growth, supports tissue repair, and modulates inflammation, particularly in the gastrointestinal tract

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For example, a 2mg study dose can be shown in the calculator as exactly 0.2mL or 20 units when using a 10mg vial with 1mL reconstitution