Blagosklonny MV (2010) Increasing healthy lifespan by suppressing aging in our lifetime: preliminary proposal
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metformin and rapamycin are not universal longevity solutions
Moderate ROS can activate PI3K/AKT and MAPK/ERK pathways to upregulate VEGF expression and VEGFR-2 phosphorylation, which further promote endothelial proliferation, migration, and vasculogenesis (71)