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The theoretical concern about its pro-angiogenic properties hasn't been validated by experimental data

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Cagrilintide has a plasma half-life of approximately 159 hours (~7 days) thanks to the acylated C20 fatty acid binding to albumin, which enables once-weekly dosing

However, it is to be noted that the results in animal models may not be similar to the results in humans

Researchers isolated and synthesized this sequence to investigate its mechanisms in controlled laboratory settings PMID: 21030672