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29 The convergence of these danger signals informs the DC about inhaled material that poses an immediate threat to pulmonary tissues and activates a maturation program: DCs process sampled antigen, present it on major histocompatibility (MHC) molecules, and strongly increase T-cell costimulatory molecule expression on their surface

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Unsuccessful smoking cessation attempts and symptoms of depression and anxiety: a systematic review and meta-analysis. For smokers worried about failure, the studys message is reassuring: relapse does not cancel progress or mean depression or anxiety will intensify

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